Cameron, B., Galbraith, S., Zhang, Y, Davenport, T., Vollmer-Conna U, Wakefield, D., Hickie, I., Dunsmuir, W., Whistler, T., Vernon, S., Reeves, WC and Lloyd, AR, for the Dubbo Infection Outcomes Study. Gene expression correlates of postinfective fatigue syndrome after infectious mononucleosis. Journal of Infectious Diseases, 2007, 196, 1, 56-66.
[Studies in the first 6 months after illness onset identified the differential expression of 733 genes in those who failed to recover, of which 234 were found to be significantly correlated with the reported severity of the fatigue symptom factor, and 180 were found to be correlated with the musculoskeletal pain symptom factor.]
Claypoole, KH., Noonan, C., Mahurin, RK., Goldberg, J., Erickson, T and Buchwald, D. A twin study of cognitive function in chronic fatigue syndrome: The effects of sudden illness onset. Neuropsychology, 2007, 21, 4, 507-513.
[CFS is associated with neuropsychological deficits across multiple cognitive domains, and in some domains — notably speed of information processing — individuals with a sudden onset of illness may be more impaired than those with a gradual onset. The reasons behind this are unclear, but they may reflect an infectious trigger and involvement of the central nervous system.]
Ter Wolbeek, M., van Doornen, LJP., Kavelaars, A, van de Putte, EM., Schedlowski M and Heijnen, CJ. Longitudinal analysis of pro- and anti-inflammatory cytokine production in severely fatigued adolescents. Brain Behavior and Immununity, 2007, May 31.
doi:10.1016/j.bbi.2007.04.007.
[CFS patients showed a distinct immune profile when compared to the severely fatigued or non-fatigued participants, i.e. increased levels of anti-inflammatory cytokines (IL-10, decreased IFN-γ/IL-10 ratio) and reduced levels of pro-inflammatory cytokines (IL-6, TNF-α) over all three time points analyzed.]
Chia, JKS and Chia, AY. Chronic fatigue syndrome is associated with chronic enterovirus infection of the stomach. Journal of Clinical Pathology, 2007, Online first: 13th September. doi: 10.1136/jcp.2007.
[Study revealing that a significant subset of CFS patients may have a chronic, disseminated, non-cytolytic form of enteroviral infection, which could be diagnosed by stomach biopsy.]
Copyright EM. Goudsmit
2007.
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Psychologist/Archivist, London.
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