Information compiled by Dr. Ellen Goudsmit.

Not to be reproduced without permission.


NOTICE BOARD

 

Candida update

A new review from an expert in the subjects casts doubt on the 'Candida' theory. The real culprit behind some of the symptoms formerly attributed to this fungus may be a bacterium. If Candida interests you, see Eaton et al, Journal of Nutritional & Environmental Medicine, 1999, 9, 4, 323-327.
 

 

Magnesium update For British patients

It's not just American specialists who regard magnesium glycinate as the oral Mg supplement of choice. I've also found a British expert who advocates this formulation. Available from practitioners only. Incidentally, several companies are currently working on a Mg solution, which may be better still. Watch this space!

St. John's Wort: not without side-effects.

While acknowledging the benefits of the herb St. John's Wort, a leader in the Lancet (1999, 354, 2014-16) has challenged claims that it's relatively risk free and virtually without side-effects. St. John's Wort (hypericum) works like other anti-depressants which reduce the reuptake of serotonin. In a sense, it's a herbal version of a class of drugs known as SSRIs, the most famous of which is Prozac. The leader makes two important points. Firstly, reports from various sources have indicated that it may interact with and reduce the effectiveness of other medications (including the pill). Secondly, taking it at the same time as prescribed antidepressants may lead to an excess of serotonin, causing tremors, headaches, myalgia, restlessness, and gastrointestinal upsets ('serotonin syndrome'). In the past, these side-effects may have been underreported or the practitioners simply avoided prescribing other medications at the same time.

The leader, written by a respected expert Prof. Ernst, suggests that patients taking St. John's Wort, should inform their doctor. However, if a (complementary) practitioner recommends a course, please don't use the warnings as an excuse not to try it. Just be aware of the possibility of side-effects, especially if you're taking other drugs. I haven't seen any reports indicating that the herb causes serious harm, but the message is that it's not risk free.     

Allergies versus adverse reactions.

Many people with ME have been told that nausea and other symptoms which occurs after a meal may be due to food intolerances or even an allergy.    However, that's not always the case. Eating is a physical activity and the body may be responding to that in the same way it responds to other forms of exertion. If you think you may have developed a sensitivity to a certain food, test it earlier in the day, when the body has more energy to spare. Or try preparing the food differently. For instance, meat may be better tolerated if it is grilled or poached rather than fried, and you may be able to eat white bread when you have difficulties with brown. In short, adverse reactions may not always represent an allergy or intolerance. (Source: various practitioners).

Tips for eating when in relapse

Avoid or if you can't, limit your intake of red meat, fried foods, fatty foods and white sugar. Eat little and often as opposed to three main meals.  Reduce coffee and other stimulants. (You probably need less stimulation, rather than more, so why not try a cup of relaxing camomile tea instead of your normal brew.) By the way, coffee can make you feel jittery about two-three hours after drinking. If you're a coffee drinker and you suffer from anxiety attacks for no apparent reason, then leave it out for three days and see if that makes a difference. Chocolate is another stimulant which may be contributing to your problems so restrict yourself to minimal amounts of a good quality (e.g. 70% solids) product. (Source: various practitioners).

Expert dismissed value of live yoghurt

Regular listeners to Michael van Straaten's programme on LBC radio may have heard Dr. John Hunter from Cambridge University dismissing the claims about live yoghurts. This well-respected gastroenterologist believes that the body reacts to probiotics in yoghurt in exactly the same way it responds to other foreign invaders. He said that the immune system simply rejects them. Apparently, the only useful bugs are those inherited from your mother. However, does this mean that all probiotics are useless?

Well, not according to a review in the Western Journal of Medicine (1999, 171, 187-191, reprinted from the BMJ). In this highly readable paper, Macfarlane (from the University of Dundee) and Cummings (from the MRC Dunn clinical Nutrition Centre in Cambridge) looked at some of the benefits of probiotics and prebiotics (e.g. fructo-oligosaccharides). They described research showing not only that certain probiotics ARE useful, but that a few have a positive effect on immune functioning. For instance, bifidobacteria induce the formation of large amounts of IgA (which helps fight cold and flu viruses).  L acidophilus and B bifidum given in capsule form to elderly people led to  appreciable changes in their inflammatory and immunological responses.  

Personally, I have not seen any evidence that live yoghurts are particularly effective in CFS.  Moreover, if you're suffering from a 'leaky gut', then it may be worth trying to sort that problem out before you start taking prebiotics or probiotics (source: Prof. Cheney).  That's why I recommend that patients seek the advice of a qualified specialist in ME, CFS and environmental medicine. Experimenting with probiotics etc may not do you harm, but it's better to do the relevant tests and see what you need, rather than guess!

Natural progesterone and bones

Suggestions that natural progesterone cream may be as effective as HRT in preventing osteoporosis have been put to the test by researchers in the States. 102 healthy post-menopausal women were given a daily dose of either Progest (progesterone cream) or a placebo.   Results after a year showed that there was a small reduction in bone mineral density in both groups of women but a significant improvement in hot flushes and sweats in the women using the active cream.  Dr. Gill Pearson is doing a similar study in the UK with a grant from the National Osteoporosis Society.  Until the results from that research is known, the evidence indicates that women should not rely on progesterone cream to prevent osteoporosis. (Source: Osteoporosis News).