The following abstracts contain research pertinent to Coherent technology. Not all applications referenced have been cleared or approved by FDA, but represent current worldwide developments and advances in laser surgery.

Orthopedics Bibliography

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Two-Year Follow-up Results of Arthroscopic Laser Surgery of the Knee: European Multicenter Study

Siebert, Saunier, Gerber, Lubbers
Techniques in Orthopaedics, 10(4):309-317


Since the early 1980s, different groups of researchers have tried to develop arthroscopic laser surgery. Laser technology may be ideal for use in arthroscopic surgery, because laser instruments are extremely small, but remain powerful. When used properly, lasers offer the arthroscopic surgeon the potential to decrease hemarthrosis, iatrogenic articular damage, and postoperative morbidity.

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Arthroscopic Subacromial Decompression With and Without the Holmium:YAG Laser. A Prospective Comparative Study

Imhoff, Ledermann
Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol. 11, No. 5 (October), 1995: pp 549-556


Because of the low level of postoperative pain, the absence of adhesions and the almost complete lack of swelling, the patients treated with the Holmium:YAG laser and without electrocautery were able to regain full range of shoulder motion sooner than those treated with shaver and electrocautery.

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The effect of Nonablative Laser Energy on Joint Capsular Properties - An In Vitro Mechanical Study Using a Rabbit Model

Hayashi, Markel, Thabit, Bogdanske, Thielke
The American Journal of Sports Medicine, Vol. 23, No. 4


To evaluate the effect of laser energy at nonablative levels on the mechanical properties of joint capsular tissues, we tested the femoropatellar joint capsules of 12 mature New Zealand White rabbits. Specimens were divided into three treatment groups (5, 10, and 15 watts) and one control group. This study demonstrates that significant capsular shrinkage can be achieved with the application of non ablative laser energy without detrimental effects to the viscoelastic properties of the tissue; although at higher energy densities, laser energy did lessen capsular stiffness properties. The results of this study should be interpreted with caution until in vivo studies are performed.

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Microdiskectomy for Lumbar Disk Herniation: A Review of 100 Cases

Lowell, Errico, Fehlings, DiBartolo, Ladosi
Orthopedics, October 1995, Vol. 18, No. 10


One hundred patients who underwent microlumbar diskectomy over 5 years were retrospectively reviewed. L4-5 and L5-S1 were compared to determine whether a patient's post-surgical outcome is related to the level where a herniation has occurred. Overall results included 70 excellent, 19 good, 2 fair, and 9 poor. Statistical analysis showed that neither the level involved, length of follow-up, nor degree of manual labor predicted outcome. Older patients and females tended to fare worse, but the trends were not significant. Three recurrent herniations occurred, 1 in the L4-L5 group and 2 in the L5-S1 group. No variable predicted recurrence.

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Lateral Retinacular Release - The Holmium:YAG Laser Versus Electrocautery

Shapiro, Fanton, Dillingham, Perkash
Clinical Orthopaedics and Related Research, No. 310, January 1995


A retrospective study was conducted in which several parameters of postoperative recovery were compared between 2 groups of patients: 25 patients who had lateral retinacular release surgery in which the Holmium:yttrium-aluminum-garnet (Ho:YAG) laser was used, and a control group of 17 patients who had the same surgery in which electrocautery was used. Postoperative recovery times of patients treated with the Ho:YAG laser were significantly decreased as compared with the recovery rates of patients in the control group. Morbidity also was reduced in the group for whom the laser was used. The results of this study indicate that the 2.1 micron wavelength, pulsed Ho:YAG laser can be used safely and effectively to perform lateral retinacular release surgery.

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Ho:YAG Laser Treatment: Good News for Athletes

Moss
Biophotonics International, February, 1995


The Holmium LACS procedure appears to represent a unique minimally invasive treatment for shoulder dislocation. Future applications may include malalignment between kneecap and the femur and torn knee cartilage. The laser is also being explored in treatment of temporomandibular joint disease, in which the jaw bone and the temporal bone of the skull grate against each other causing extreme facial pain and headaches. The Holmium laser is a powerful yet precise and safe tool easily adapted for use in arthroscopic surgery. Thermal modification of capsular tissue by this procedure may be useful in treating GHI resulting from capsular redundancy. Further study is in progress to optimize tissue shrinkage and tissue strength.

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Laser "Shrinks" Shoulder Capsule Tissue

Orthopedics Today, May 1994, Vol. 14, No. 5

A group of orthopedic surgeons is working assess the use of the Holmium:YAG laser in correcting glenohumeral instability. By using the laser to "shrink" tissue in the shoulder capsule, function and mobility are restored to patients. The procedure, dubbed laser assisted capsular shift (LACS), is being described as a "potentially promising alternative" to the variety of techniques that currently address glenohumeral instability.

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Wavelength Selection in Laser Arthroscopy

Meller, Black, Sherk, Uppal, Rhodes
ASLMS ABSTRACTS


To compare electrosurgical devices and various laser wavelengths in their acute effects on human meniscal tissue. CO2, sapphire contact tip Nd:YAG, Ho:YAG, and excimer laser wavelengths cause little thermal damage to meniscal tissue in vitro and appear superior to electrosurgical devices and freebeam Nd:YAG lasers. This study shows that CO2, contact Nd:YAG and excimer laser wavelengths can be used to cut, sculpt and ablate fibrocartilage or hyaline cartilage safely and effectively.

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Arthroscopic Synovectomy

Smiley, Wasilewski
Arthroscopy: The Journal of Arthroscopic and Related Surgery, 6(1):18-23


This study was undertaken to evaluate the efficacy of knee synovectomy with arthroscopic technique. Nineteen patients with 25 operated knees were studied. All 25 knees had 6-month follow-up, 21 knees had 2-year follow-up, and 14 knees were evaluated at least 4 years after operation. After operation, patients were evaluated using clinical data including pain relief, functional capacity, range of motion, recurrent synovitis, and presence of effusion. Preoperative as well as follow-up weight bearing radiographs were also studied to assess the results of this procedure. At 6 months' postoperative clinical evaluation, 96% of patients showed good results. At 2 years, 90% of patients were considered to have good results, and at 4 years, 57% of patients continued to do well. Of those knees studied radiographically, 81% showed no progressive radiographic changes at 2 years and 61.5% showed no deterioration at 4 years. Clinical results correlated well with radiographic results. Arthroscopic synovectomy yielded results similar to those previously published for open synovectomy, with less operative and postoperative morbidity.

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Lasers in Orthopaedic Surgery

Garrick

At the present time, lasers offer the orthopedist little beyond what can be accomplished by well-established mechanical means. Most unique are the arthroscopic laser delivery systems that allow cutting or ablation in areas difficult to access with mechanical instruments. Perhaps unique is the precision with which some lasers ablate diseased tissue, although the sparing of one or two mm of meniscus or articular cartilage may be of negligible clinical importance. Most disturbing, however, is the burgeoning availability and use of lasers in orthopedics despite the paucity of scientific documentation regarding their efficacy.

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Laser-Tissue Interactions and Laser Osteotomy

Sherk, Kollmer
Lasers in Orthopaedics, Chapter 5


The effects of lasers on cartilage, tendon, and other tissues are described in chapters on arthroscopy (chapter 9) and tissue welding* (chapter 8) The effects of lasers on bone tissue and laser osteotomy justify separate discussion.

* Application not cleared for use in the U.S.

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Holmium Laser Surgery

Dillingham, Price, Fanton
Orthopedics, Vol. 16, No. 5, pp 563-566


This relatively new form of laser energy, with its powerful and precise ability to ablate the dense tissues of the musculoskeletal system as well as its transmissibility in fiberoptic cables and a fluid medium, makes this an ideal tool for use in orthopedic surgery. Its importance as a new orthopedic modality may well lie in its unique ability to gain access to small articular compartments while providing superior homeostatic control, thereby decreasing postoperative morbidity. While not yet in widespread use, its popularity is rapidly spreading and research into a variety of new applications is growing steadily.

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Histology and Arthroscopic Anatomy of the Ulnar Collateral

Timmerman, Andrews
American Journal of Sports Medicine, Vol. 22, No. 5, 1994


The histology and arthroscopic anatomy of the ulnar collateral ligament of the elbow were studied in cadaveric specimens. The capsule consists of two layers of collagen fibers, with two distinct ligamentous bundles corresponding to anterior and posterior portions of the ulnar collateral ligament. The posterior bundle consists of distinct collagen bundles within the layers of the capsule; the anterior bundle consists of a similar thickening with the capsular layers, with an additional ligament complex superficial to the capsular layers. With arthroscopy only the anterior 20% to 30% of the anterior bundle of the ulnar collateral ligament could be visualized via the anterior portal. Only the posterior 30% to 50% of the posterior bundle could be seen via the posterior portals. After sectioning of the anterior bundle, joint instability was noted arthroscopically by an increased opening in the ulnohumeral joint with application of valgus stress.

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Arthroscopic Treatment of Post-traumatic Elbow Pain and Stiffness

Timmerman, Andrews
American Journal of Sports Medicine, Vol. 22, No. 2, 1994


Nineteen consecutive cases of posttraumatic arthrofibrosis of the elbow secondary to a fracture or fracture-dislocation and treated with arthroscopic debridement and manipulation were retrospectively reviewed. All of the patients had pain and stiffness in their elbows, and all had failed a conservative therapy program. all 19 patients were followed postoperatively for an average of 29 months (range, 12 to 51). One hundred-point scoring systems were used to evaluate subjective (pain, swelling, locking, and activities) and objective (range of motion) results. The average preoperative subjective score of 39 improved to 91 postoperatively (P=.0001); the objective score improved from 46 preoperatively to 81 postoperatively (P=0.0001). Extension improved from a mean of 29 to 11 degrees; flexion improved from an average of 123 to 134 degrees. Fourteen patients had limitations in their sports activity preoperatively; 11 were able to return to their pre-injury levels of activity after surgery. This study demonstrated good-to-excellent overall results in 79% of the patients treated with arthroscopic debridement for posttraumatic elbow arthrofibrosis.

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A Literature Review of Lasers and Articular Cartilage

Vangsness, Ghaderi
Orthopedics, May 1993, Vol. 16, No. 5, pp 593-598


Articles from the English literature concerning lasers and articular cartilage were reviewed. Different experimental methods and laser systems were analyzed. Many studies lacked scientific validity. Future investigations with sound biologic foundations are recommended.

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Arthroscopic Capsular Release of Flexion Contractures (Arthrofibrosis) of the Elbow

Jones, Savoie
Journal of Arthroscopic and Related Surgery, Arthroscopy, Vol. 9, #3, 1993, pp 277-283


Twelve patients with flexion contractures of the elbow were managed by arthroscopic release of the proximal capsule and debridement of the olecrasnon fossa. Postoperatively the mean flexion contracture improved from 38 to 3 degrees with supination improving from 45 to 84 degrees and pronation improving from 80 to 88 degrees. All patients reported a decrease in pain level as well as improvement in motion. There was one severe complication in this series, in which a patient sustained a permanent posterior interosseous nerve palsy.

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Use of Lasers in Orthopedic Surgery: Current Concepts

Abelow
Orthopedics, May 1993, Vol. 16, No. 5, pp 551-556


A surgical laser is a new, multipurpose tool that can cut, coagulate, and vaporize tissues. It utilizes a low profile handpiece that allows easy access to tight places and small joints. The Holmium laser at 2.1 µm wavelength is gaining wide acceptance among orthopedic surgeons as a useful arthroscopic surgical tool. It has a minimal amount of thermal necrosis and is able to cut and ablate tissues with great ease. Current investigation with laser tissue&endash;agglutination* and tissue welding*&endash;may make it possible to repair torn tissues with laser energy.

* Application not cleared for use in the U.S.

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Laser Therapy: Scientific Basis and Clinical role

Basford
Orthopedics, May 1993, Vol. 16, No. 5, pp 541-547


This review first examines the 25-year history and scientific basis for laser therapy. Clinical applications are discussed and the reasons for its relative lack of acceptance in the US are examined. The article concludes with an overview of current research and the impact it will have on laser therapy's role in US clinical practice.

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Glenohumeral Instability: Evaluation and Treatment

Pollock, Bigliani
Journal of the American Academy of Orthopaedic Surgeons, 1993; 1:24-32


Glenohumeral instability encompasses a spectrum of disorders of varying degree, direction, and etiology. The keys to accurate diagnosis are a thorough history and physical examination. Plain radiographs are frequently negative, especially in subtle forms of instability. Computed tomography (CT), CT arthrography, magnetic resonance imaging, arthroscopy, and examination under anesthesia may occasionally yield important diagnostic information. Non-operative treatment of shoulder instability consists of reduction of the joint (when necessary), followed by immobilization and rehabilitative exercises. The length and the value of immobilization remain controversial.

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Comparison Between Laser Meniscectomy with Excimer and Ho:YAG Lasers

Marcacci, Buda, Zaffagnini, Visani, Iacono, Strocchi, dePasquale
Journal of Clinical Laser Medicine & Surgery, Volume 11, Number 1, 1993


The authors report their experiences using the excimer laser and Holmium:YAG laser in arthroscopic meniscal surgery. Histologic and ultrastructural aspects caused by laser irradiation on meniscal tissues are evaluated. Two groups of 10 patients, each suffering from a bucket-handle lesion of the internal meniscus, were used for this study. The histologic results of the study confirm the clinical reliability of the laser even in the presence of different ultrastructural frames.

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Foreign Body Arthroscopically Retrieved from the Elbow

Cameron, Travis, Kruse
Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol. 9, No. 2, 1993


A patient was found to have a tea-cup handle fragment in her elbow joint. The fragment was removed arthroscopically. Interestingly, the patient was unaware of its presence and was asymptomatic for >29 years.

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The use of Lasers in Orthopaedic Procedures

Sherk
Journal of Bone and Joint Surgery, Vol. 75-A, No. 5, May 1993


This article explains history of laser including basic laser physics, arthroscopy, discectomy, removal of polymethylmethacrylate*, tissue welding*, biostimulation* and treatment of tissue defects, photodynamic treatment of tumors with lasers, and safety and credentialing.

 

* Application not cleared for use in the U.S.

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Lasers in Arthroscopic Surgery (Laseranwendung in der Arthroskopie) in German

Siebert
Orthopade, (1992) 21:273-288


Arthroscopic surgery has become a routine procedure, thanks to the availability of excellent video systems and the development of new and efficient instruments. Since early 1980 several groups have been developing arthroscopic laser surgery. Laser technology is ideal for use in endoscopic surgery because lasers are potentially extremely small but nevertheless powerful tools with many advantages. Lasers are used in arthroscopy not only to divide tissue but also to smoothen cartilage, for hemostasis, for percutaneous lumbar and cervical disc surgery, for photodynamic therapy, for tumor therapy and in diagnosis. Lasers must now show, in prospective clinical studies, that their theoretical advantages are matched in practice.

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The Use of the Holmium Laser in Arthroscopic Surgery

Fanton, Dillingham
Seminars in Orthopaedics, Vol. 7, No. 2, June, 1992


The Holmium laser has been found to be a safe, effective arthroscopic tool for peripheral joint surgery. Its multiple applications, small probe size, fiberoptic capability, and fluid medium transmissibility with pulsed, freebeam delivery offer significant advantages over electrocautery and laser systems developed for other biomedical applications. The 2.1 µm wavelength appears to ideally suited for arthroscopic use, and the recent development of improved delivery devices and the new high power output 32W system will continue to provide greater versatility and speed of use and will broaden an already seemingly limitless scope of applications.

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Holmium:Yttrium-Aluminum-Garnet Laser Versus Carbon Dioxide Laser Versus Mechanical Arthroscopic Debridement

Lane, Sherk, Mooar, Lee, Black
Seminars in Orthopaedics, Vol 7, No. 2, June 1992


Regardless of the method used, the time required for a patient to return to function was approximately 4 weeks. With all factors being considered, this study lends support to the use of Ho:YAG or CO2 lasers as an effective means for arthroscopic partial meniscetomy or chondroplasty. It is unlikely that lasers will completely replace mechanical instrumentation in arthroscopy; however, they are quickly becoming a useful addition to the armamentarium of arthroscopists.

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Neodymium:Yttrium-Aluminum-Garnet Contact Laser Arthroscopy

O'Brien, Fealy, Miller Seminars in Orthopaedics, Vol. 7, No. 2, June 1992

Biomedical Technology and the corresponding development of surgical instrumentation has played an integral role in the evolution of orthopaedic surgery. Advances in orthopaedic surgical instrumentation have made the orthopaedist's job much easier, efficient, and effective. The trend has been toward minimally invasive therapeutic interventions that achieve identical or superior clinical results as prior techniques.

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Early Response of Canine Temporomandibular Joint Tissues to Arthroscopically Guided Neodymium:YAG Laser Wounds

Bradrick, Eckhauser, Indresano J Oral Maxillofac Surg, 50:835-842, 1992

A Neodymium yittrium aluminum garnet (Nd:YAG) laser inserted through an operating arthroscope was used to introduce applied energy to synovial tissues, articular discs, and bone in the temporomandibular joint of mongrel dogs. Arthroscopic inspection of the wounds was performed at 1 and 2 weeks postoperatively. The animals were killed and the temporomandibular joints were examined grossly and histologically to determine the extent of injury and healing. The results show that laser wounds of bone and articular disc undergo no repair, whereas laser wounds of synovium show rapid repair. Laser damage to condylar marrow under an articular disc wound was unexpectedly found.

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Gas Bubble Technique in Laser Arthroscopic Surgery

Smith, Johansen, Vangsness, Marshall, Sutter, Bonavelet Seminars in Orthopaedics, Vol. 7, No. 2, June 1992

The gas bubble technique is a technique for use in arthroscopic laser surgery. The CO2 laser is an efficient energy delivery system in gas arthroscopy and has been highly successful. However, most arthroscopic surgeons in the United States prefer saline arthroscopy. The passage of CO2 gas through the CO2 energy delivery system allows for a microenvironment of CO2 between the tool and the target with a macroenvironment of saline to allow saline arthroscopy. No complications have been encountered to date with the gas bubble technique.

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Laser Arthroscopy

Sherk, Lane, Black
Orthopaedic Review, September 1992


Lasers have become widely used in several medical and surgical disciplines. In ophthalmology and plastic surgery, their use has permitted the development of therapeutic modalities that would have been otherwise impossible. In such specialties as gynecology and general surgery, lasers provide advantages that make certain procedures more convenient and easier to perform. In contrast, orthopaedic surgeons have, to date, been slow to accept these devices into the therapeutic armentarium. The purpose of this paper is to describe the status of laser use in the orthopaedic subspecialty of arthroscopy.

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Holmium Laser Arthroscopy Opens New Frontier for Orthopedics

Owens, Zacherl
Laser Nursing, Volume 5, Number 3, 1991


Remarkable advances in laser surgery have been made in the past decade. Surgeries that previously required major incisions and recovery periods of days or weeks have become outpatient procedures with significantly shorter recovery times. As concern over the high cost of health care increases, the medical profession is adopting the least traumatic and most cost-effective procedures available. To the patient, laser surgery can mean a shorter hospital stay, a more rapid recovery period, and a faster return to normal daily activities.

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Thermal Injury Resulting from Arthroscopic Lateral Retinacular Release by Electrocautery: Report of Three Cases and a Review of the Literature

Lord, Maltry, Shall
Arthroscopy ,1/1/91


This article reports three cases of full thickness thermal burns of the skin in the 85 cases of arthroscopic lateral retinacular release we performed using electrocautery. To our knowledge, this complication has not previously been reported.

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Soft Tissue Effects of the Holmium - YSGG Laser in the Canine Trachea

Shapshay, Maretz, Setzer
Otol. - Head and Neck Surgery, 1/1/90


A Holmium-yttrium scandium gallium garnet laser is a pulsed midinfrared crystalline laser (wavelength, 2.1 µm ), which is easily transmissible through flexible quartz fibers. With use of a 300 µm fiber delivery system, this laser was applied in the canine trachea to create a standard 5-mm diameter lesion through mucosa and submucosa. Power settings of 400 mJ and 600 mJ per pulse at 2 pulses per second were used, and wound healing was studied over a 2-week period. Excellent control of depth of tissue ablation was noted, with uncomplicated wound repair. Although healing was somewhat slower compared with healing when the CO2 laser was used, less granulation and fewer inflammatory changes were noted.

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Comparison of Methods for Transcatheter Fragmentation of Gallstones

Johnson, Oz, Chuck, Treat
Surg Endosc, 1989


Alternative methods have been considered for treating cholelithiasis. The three devices used for cholecystolithotripsy were the ultrasonic lithotriptor (UL), the electrohydraulic lithotriptor (EHL), and the Thulium-Holmium-Chromium:YAG laser (THC:YAG). The UL effectively fragmented all types of stones studied, although it is necessary to hold the stone against the tip of the probe. The EHL quickly fragmented noncalcified and pigment stones simply by placing the tip in the vicinity of the stone, but calcified stones had to be held in position near the electrode. The THC:YAG was effective at fragmenting each type of stone, but the number of pulses required was quite large, corresponding to 7 min for some stones. Because of the specific advantages and disadvantages of each device, a combination of devices may be required for successful clinical cholecystolithotripsy.

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Nucleus Pulposus Vaporization - Experimental Investigations on Use of Lasers on the Intervertebral Disc

Siebert, Wirth
Percutaneous Lumbar Discectomy, 1989


The search for a less invasive method of treatment which hardly burdens the patient has become important not least in view of studies which criticize the effectiveness of chemonucleolysis (9, 11). The fundamental idea of nucleus pulposus vaporization was to reduce by direct vaporization the optically very homogeneous properties of the nucleus pulposus, which differ substantially from the annulus fibrosis at least in healthy person, and thus to attain decompression in the intervertebral disc concerned. At the same time, it was hoped that this technique would disturb the stability of the movement segments as little as possible owing to the small operation and the selective technique.

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Effects of Varying Intensities of laser Energy on Articular Cartilage: A Preliminary Study

Schultz, Krishnamurthy, Thelmo, Rodriguez, Harvey
Lasers in Surgery and Medicine, 1985, Vol. 5


The effects of laser energy on articular cartilage were studied utilizing the Neodymium:Yag laser. Animals were killed at weekly intervals from 1 to 6 weeks, the knees exposed to 25 and 75 J demonstrated a reparative process with chondral proliferation. The knees exposed to 125 J demonstrated fiberoptic tissue and tissue necrosis that resulted in fibrosis. In the knees not exposed to laser and tissue necrosis that resulted in fibrosis. In the knees not exposed to laser energy, numerous foci of granulation tissue were present at all stages with the end point of healing being one of fibrosis with disorganized patchy cartilage islands.

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Laser Energy in Arthroscopic Meniscectomy

Whipple, Caspari, Meyers
Orthopedics, September 1983, Vol. 6, No. 9


Rationale and technique are discussed for performing arthroscopic meniscectomy with a carbon dioxide laser, including presentation of findings in limited rabbit and human studies.

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The Bankart Procedure

Carter R Rowe, M.D., Dinesh Patel, M.D.William W. Southmayd, M.D. The Journal of Bone and Joint Surgery January 1978, Volume 60-A, No. Of 161 patients with 162 shoulders operated on during a thirty-year period (1946 to 1976), 124 were re-examined and 21 answered a questionnaire. The lesions found at surgery were separation of the capsule from the anterior glenoid rim in 85%, a Hill-Sachs lesion of the humeral head in 77%, and damage to the anterior glenoid rim (including fracture) in 73%. There were five recurrences (3.5%) after repair by the method described in the 145 shoulders that were followed. Only one of the 46 patients with dislocation on the dominant side and one of the 31 with dislocation on the non-dominant side failed to return to the competitive athletic activities in which they had participated prior to injury. We concluded that with the meticulous technique of the Bankart repair as described, postoperative immobilization is not necessary, early return of motion and function can be expected, and resumption of athletic activities with no limitation of shoulder motion is possible for most patients.

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Spontaneous Osteonecrosis of the Knee and Medial Meniscal Tears

Norman, Baker Diagnostic Radiology, December 1978

Several factors may play a role in the etiology of spontaneous osteonecrosis of the medial femoral condyle. Corticosteroids are unknown to induce osteonecrosis, and 45% of the patients in this study received steroids parenterally or by intra-articular injection. Another factor, heretofore given little attention, is the association of medial meniscal tears and spontaneous osteonecrosis. Twenty-one (78%) of 27 knees examined by arthrography demonstrated meniscal tears. Stress concentration over the edge of the meniscal fragment may result in ischemic necrosis of the femoral condyle. Early detection of a medial meniscal tear by arthrography in older patients and prompt treatment may be important in avoiding the late changes of spontaneous osteonecrosis.

 

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